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| 題 名 | Simultaneous Determination of Morphine HCl, Ketamine HCl and Droperidol in 0.9% Sodium Chloride by HPLC=以高壓液相層析法同時分析0.9%氯化鈉水溶液中Morphine HCl、Ketamine HCl及Droperidol |
|---|---|
| 作 者 | 李貫棠; 丘宏治; 王大鵬; | 書刊名 | 藥物食品分析 |
| 卷 期 | 13:1 2005.03[民94.03] |
| 頁 次 | 頁93-95+100 |
| 分類號 | 341.95 |
| 關鍵詞 | 0.9%氯化鈉水溶液; 高壓液相層析; Morphine HC1; Ketamine HC1; Droperidol; 0.9% sodium chloride; HPLC; |
| 語 文 | 英文(English) |
| 中文摘要 | 於強酸、鹼及過氧化條件下,以高壓液相層析之安定性指示分析法,可同時定量0.99志氣化納水溶液中之morphine HCl、ketamine HCl及droperidol。本法採用BDS C18層析管柱 (3.9mm × 15cm) ,移動相之組成為甲醇/乙腈/0.01M 1-octane sulfonic acid sodium於0.005M磷酸緩衝溶液 (pH4.0) (50/50/100) ,紫外線偵測器設定於254nm,共良好之選擇性及專一性。 |
| 英文摘要 | A simple and rapid liquid chromatographic method is presented for the determination of morphine HCl, ketamine HCl and droperidol in 0.9% sodium chloride injection stored in polyvinyl chloride (PVC) infusion bags. Assay was performed on a pre-packed HPLC Hypersil BDS C18 3.9 mm X 15 cm, particle size 3 mm column under controlled ambient temperature. Separation among morphine HCl, ketamine HCl, droperidol and their associated degradation compounds was achieved by isocratic elution using mobile phase consisting of methanol/acetonitrile/0.01 M 1-octane sulfonic acid sodium in 0.005 M phosphate buffer (pH 4.0) (50/50/100) at a flow rate of 1.0 ml/min. An UV/VIS variable programmable wavelength detector set at 254 nm was used. Sample volumes of 20 mL were injected. There was no need for sample pre-treatment. |
本系統中英文摘要資訊取自各篇刊載內容。