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題名 | Henoch-Schonlein Purpura with Hemorrhagic Bullae in Children: Report of Two Cases=與兒童過敏性紫斑症相關的出血性水疱:兩病例報告 |
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作者 | 柳博邁; 黃振南; 陳信旭; 黃懿娟; 黃昭誠; 楊崑德; 王志祿; | 書刊名 | 微免與感染雜誌 |
卷期 | 37:6 2004.12[民93.12] |
頁次 | 頁375-378 |
分類號 | 417.5637 |
關鍵詞 | 兒童; 過敏性紫斑症; 出血性水疱; Hemorrhagic bullae; Henoch-schoenlein purpura; Leukocytoclastic vasculitis; Vesiculobullous skin diseases; |
語文 | 英文(English) |
英文摘要 | Henoch-Schonlein purpura (HSP) is the most common form of acute vasculitis primarily affecting children. Clinical features include skin rashes, arthritis, abdominal pain and nephritis. Skin biopsy on immunofluorescence often reveals granular depositions of immunoglobulin A (IgA) and C3 within the walls of the dermal vessels as well as in the connective tissue of the upper dermis. The diversity of skin rashes produces confusion in diagnosis of HSP, especially in the presence of bullous lesions. Bullous lesions are very rare in children with HSP, whereas they often appear in adults with HSP. We report 2 cases of HSP in whom hemorrhagic bullae manifested predominantly. In our report, the skin biopsies of both patients revealed typical leukocytoclastic vasculitis without IgA and complement depositions on direct immunofluorescence studies. Dramatic improvement of clinical symptoms and signs was observed within a few days after corticosteroids were administered. There was neither recurrence nor nephritis in these 2 patients. |
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