查詢結果分析
相關文獻
- Clinical Features of Type 1 Diabetic Children at Initial Diagnosis
- 病例報告及病患用藥指導--小兒科加護病房兒童糖尿病酮酸血症
- Child Transitional Object Attachment: Nature, Development, and Related Factors
- 散布性交易訊息刑罰化合憲否
- Fulminant Type 1 Diabetes Mellitus Leading to Fetal Loss in a Pregnant Chinese Woman
- Clinical and Laboratory Characteristics of Type 1 Diabetes in Children and Adolescents: Experience from a Medical Center
- 照顧一位初次診斷第1型糖尿病兒童之護理經驗
- 兒童糖尿病自我管理之概念分析
- 兒童知覺動作發展
- 聯合國與盧安達人權:滅絕種族及其他罪行之懲治
頁籤選單縮合
| 題 名 | Clinical Features of Type 1 Diabetic Children at Initial Diagnosis=臺灣第1型糖尿病兒童初發病時的臨床特徵 |
|---|---|
| 作 者 | 羅福松; 楊敏慧; 張鑾英; 歐湧淳; 范揚灝; | 書刊名 | 臺灣兒科醫學會雜誌 |
| 卷 期 | 45:4 民93.07-08 |
| 頁 次 | 頁218-223+257 |
| 分類號 | 417.5937 |
| 關鍵詞 | 第1型糖尿病; 兒童; 酮酸血症; Type 1 diabetes mellitus; T1DM; Children; Ketoacidosis; |
| 語 文 | 英文(English) |
| 中文摘要 | 我們分析及比較了從19931至2003年在長庚兒童醫院剛發病的165位糖尿病兒童的基本資料、臨床症狀、及實驗數據;發病年齡分佈在0-1歲19人(11.5%),2-4歲39人(23.6%),5-9歲61人(37%)及10-16歲46人(27.9%);發病月份顯示秋冬是高峰,而夏季是穀底,但未達統計關差異(x^2=1.86,p=0.61);常見的發病症狀依序爲多喝、體重下降、多尿、及疲倦;幼小病童容易以喘來表現及具較低的C-peptide、糖化血色素;GAD抗體及胰島素自體抗體的盛行率分別爲67%及49%;嚴重型酮酸血症病童通常較幼小(但未達統計差異)、先前發燒病史、較低的T4、T3血清濃度及較高的總白血球。結論是年幼的糖尿病兒童所佔比充不低,而且常有較嚴重的胰島素缺乏;年幼及先前發燒病史可以誘發嚴重的酮酸血症,高度的警覺性可以及早診斷及治療。 |
| 英文摘要 | Clinical and laboratory data of 165 newly diagnosed diabetic children at Chang Gung Children’s Hospital in Taiwan from 1993 to 2003 were analyzed. The age distribution was categorized as 0-1 years: 19(11.5%), 2-4 years: 39 (23.6%), 5-9 years: 61 (37%), and 10-16 years: 46 (27.9%); the incidence showed spring/winter peak and a mid-summer trough but not statistically significant (x^2=1.86, p=0.61). The most common symptoms on presentation were polydipsia, weight loss, polyuria, and fatigue. Very young diabetic children had a higher incidence of having dyspnea at presentation (p=0.029) and had significantly lower levels of C-peptide (p=0.0086) and HbAlc (p=0.0025). The prevalences of GAD antibody and insulin autoantibodies were 670o and 49%, respectively. Children with severe diabetic ketoacidosis (DKA) were younger at diabetes onset (p=0.36, not to the statistical significance), had a higher incidence of preceding febrile illnesses (p=0.05), lower T4 and T3 levels (p=0.0008, 0.02), and higher white blood cell counts (p=0.03) than the mild group. In conclusion, diabetes in very young children is not rare and is more associated with more severe insulin deficiency. Young age at diabetes onset and preceding febrile illness may provoke severe DKA. High alertness is necessary for prompt diagnosis and management. |
本系統中英文摘要資訊取自各篇刊載內容。