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題名 | Giant Cell Arteritis with CD8+ instead of CD4+ T Lymphocytes as the Predominant Infiltrating Cells in a Young Woman=一例年輕女性的巨細胞血管炎:主要的浸潤細胞為CD8+而非CD4+T淋巴球 |
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作者 | 吳建陞; 許寬立; 張逸良; 李光倫; | 書刊名 | 微免與感染雜誌 |
卷期 | 37:4 2004.08[民93.08] |
頁次 | 頁246-249 |
分類號 | 415.74 |
關鍵詞 | 巨細胞血管炎; 浸潤細胞; 淋巴球; Aneurysm; CD8+ T-lymphocytes; Giant cell arteritis; Pulmonary veins; Sensorineural hearing loss; Takayasu's arteritis; |
語文 | 英文(English) |
英文摘要 | Giant cell arteritis is rarely reported in people aged less than 50 years. We report a case of giant cell arteritis in a woman who developed symptoms of dizziness, headache, bilateral sensorineural hearing impairment, and had 1 episode of transient left hemiparesis before the age of 30. Carotid angiography showed multiple segmental narrowing in cranial vessels. Subsequently, at the age of 31, she had weight loss and developed a fever. Chest radiograph revealed mediastinal widening, and chest computed tomography revealed dilated pulmonary arteries and veins. Coronary angiography and aortography showed irregular narrowing of the descending aorta and multiple stenosis, with aneurysmal dilatation involving the proximal and distal coronary, pulmonary and mesenteric arteries. Multinucleated giant cells and predominant CD8+ T lymphocyte infiltration were noted in a left temporal artery biopsy specimen. The patient’s age and the finding of dilated pulmonary veins and prominent CD8+ T lymphocytes in the biopsy specimen suggest that this case was a distinct form of systemic giant cell arteritis. |
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