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頁籤選單縮合
題 名 | Adrenal Incidentalomas in Taiwan: High Prevalence and Malignancy Rate=在臺灣的腎上腺偶發瘤--高惡性比例及高盛行比率 |
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作 者 | 王誌慶; 黃禹堯; 林仁德; 薛純; 朱聖賢; | 書刊名 | 長庚醫學 |
卷 期 | 26:1 2003.01[民92.01] |
頁 次 | 頁34-40 |
分類號 | 415.934 |
關鍵詞 | 腎上腺偶發瘤; 庫欣氏症; 原發性多醛酮症; 腎上腺惡性腫瘤; Adrenal incidentaloma; Cushing's syndrome; Primary aldosteronism; Adrenal malignancy; |
語 文 | 英文(English) |
中文摘要 | 背景:腎上腺包含三層皮質及髓質。其具多種荷爾蒙分泌的特性,造成臨床表現的多樣性。為了研究腎上腺腫瘤在臺灣人的表現,因此我們將長庚醫院病理診斷確定的腎上腺腫瘤加以分析。 方法:我們分析從1983到2000年258位有腎上腺腫瘤且其資料完整的病人,其中174例是功能性而84例是非功能性。其診斷主要是根據臨床表現、賀爾蒙狀況,影像檢查及病理報告。 結果:258位病人中,包括161位乘性(平均年齡:38.5±15.4歲)及97位男性(平均年齡:41.6±17.8歲)。腎上腺皮質腫瘤的盛行率好性比男性高。52%病人診斷年紀在30-50歲之間。在所有腫瘤中,無症狀之偶發瘤佔1/3(84例),且46例惡性腫瘤中40例(87%)是偶發瘤。所有惡性腫瘤直徑均大於3公分。術後腎上腺功能不足有18%、死亡率為0.4%。 結論:在我們的系列,偶然發弄的腎上腺腫瘤約佔腎上腺皮質腫瘤的三分之一,及惡性腫瘤的87%。因此在臺灣對腎上腺偶發瘤應提高注意,而直徑大於3公分的歸發瘤則應該接受病理檢查。 |
英文摘要 | Background: The endocrine adrenal gland has 3 zones comprised of the cortex and medulla. The character of multi-hormonal expression results in multiple clinical manifestations. To define the clinical characteristics of adrenal tumors in Taiwan, we reviewed 336 pathologically proven adrenal tumors at Chang Gung Memorial Hospital in Linkou. Methods: We retrospectively analyzed 258 pathologically proven adrenal tumors with sufficient data treated from 1983 to 2000. Among them, 174 (67%) were functional and 84 (33%) were nonfunctional. The diagnosis was based on clinical features, hormonal status, imaging studies, and pathology. Results: Of the 258 patients, 161 were women (mean age, 38.5±15.4; range, 1-75 years) and 97 men (mean age, 41.6±17.8; range, 1-81 years). The prevalence of cortical tumors was much higher in females than in males. Fifty-two percent of patients with an adrenal were diagnosed at an age between 30 and 50 years. Incidentalomas (N=84) accounted for about 1/3 of total tumor cases. Of the 46 cases proven to be malignant, 40 (87%) were found incidentally. All maliganant tumors had a diameter of greater than 3 cm. Postoperative adrenal insufficiency was present in 18% of cases, and overall mortality in this study was 0.4%. Conclusions: In our series, adrenal incidentalomas corresponded to about 1/3 of adrenal tumors and accounted for 87% of malignancies. It is mandatory to increase medical attention for incidentally found adrenal masses in Taiwan. Those incidentalomas with a diameter of more than 3 cm should undergo a pathological examination. |
本系統中英文摘要資訊取自各篇刊載內容。