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題名 | Thrombocytopenia Following Tirofiban Therapy after Coronary Stenting--A Case Report=冠狀動脈支架手術時使用Tirofiban後引發血小板減少、出血等併發症--一病例報告 |
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作者 | 任勗龍; 殷偉賢; 楊茂勳; Jen, Hsu-lung; Yin, Wei-hsian; Young, Mason Shing; |
期刊 | 中華民國重症醫學雜誌 |
出版日期 | 20020400 |
卷期 | 4:2 2002.04[民91.04] |
頁次 | 頁101-106 |
分類號 | 418.22 |
語文 | eng |
關鍵詞 | 血小板醣蛋白Ⅱb/Ⅲa拮抗劑; 血小板減少; 冠狀動脈介入治療; 支架; Platelet glycoprotein Ⅱb/Ⅲa inhibitor; Thrombocytopenia; PCI; Stent; |
中文摘要 | 臨床研究顯示使用血小板醣蛋白Ⅱb/Ⅲa拮抗劑,可以顯著改善急性冠狀動脈症候群患者接受冠狀動脈介入治療之預後。該藥物雖可能影響血小板功能。但臨床上出現急性之血小板數目下降及明顯之出血併發症者則很少見。本文報告一例不穩定心絞痛病患,在接受右冠狀動脈支架手術及醣蛋白Ⅱb/Ⅲa拮抗劑Tirofiban ,不幸發生急性血小板減少及出血併發症之病例。在立即停用該藥及肝素後,病人臨床出血停止且其血小板數目亦恢復正常。 |
英文摘要 | Many clinical trials have proved that treatment with inhibitors of the platelet glycoprotein Ⅱb/Ⅲa significantly improves outcomes of patients with acute coronary syndrome and during percutaneous coronary intervention (PCI). However, bleeding complications and thrombocytopenia occur in a small percentage of patients. We report a case of unstable angina who received coronary stenting and Tirofian infusion for right stenotic coronary artery. Fever, chill, oral bleeding, hemoptysis and thrombocytopenia all developed after Tirofiban infusion. The patient recovered after discontinuation of Tirofiban and heparin. Platelet count returned to normal range during the follow-up period. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。