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題名 | Transient Acantholytic Dermatosis (Grover's disease)--A Case Report=短暫性表皮棘層鬆解症--病例報告 |
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作者 | 鄭裕文; 邱耀堃; 何宜承; 陳維仁; Cheng, Yu-wen; Chiu, Yao-kun; Ho, Ji-chen; Chen, Wei-jen; |
期刊 | 中華皮膚科醫學雜誌 |
出版日期 | 20000900 |
卷期 | 18:3 2000.09[民89.09] |
頁次 | 頁229-234 |
分類號 | 415.68 |
語文 | eng |
關鍵詞 | 短暫性表皮棘層鬆解症; Transient acantholytic dermatosis; Grover's disease; Acantholysis; Acrosyringium; Sweating; |
中文摘要 | 我們在此報告一例短暫性表皮棘層鬆解症。病人是因肺部膿瘍而住院,住院第五天時,在病人軀幹及上臂出現具癢感的紅色丘疹及丘疹性水疱(papulovesicle)。皮膚切片之組織病理學檢查呈現類似尋常性天疱瘡之水疱變化。病人的肺部問題經治療後漸漸改善,不再發燒。在這同時,皮膚病灶經使用口服抗組織胺及外用類固醇藥膏治療後兩週內消失。將檢體連續的切片(serial sectioning),做進一步的組織病理學檢查,發現兩個局限之小水疱剛好都在汗管開口處。這個病例在臨床及組織病理學上的變化都極為符合與熱及流汗有關。這可是台灣文獻上正式報告的第一例。台灣罕見有這種病例之報告,可能是因為東方人的盛行率較低,或是因為不熟悉這個病而忽略了它的診斷。我們建議當遇到這種病例時,可將檢體做連續的切片,觀察它的組織病理變化與汗管開口的關連性。 |
英文摘要 | We herein report a case of transient acantholytic dermatosis (TAD) occurring in a patient with lung abscess. He developed pruritic erythematous papules and papulovesicles on the trunk and upper arms on the fifth hospital day. The histology of skin biopsy showed small circumscribed blisters with a pemphigus vulgaris-like pattern. Under medical treatment, he became afebrile on the tenth hospital day. In the mean time, oral antihistamine and topical steroid cream were prescribed for the skin lesions and the eruption cleared in two weeks. Serial sectioning of the biopsy specimen revealed that the two suprabasal blisters were simultaneously associated with the acrosyringium. The clinicohistologic findings in this case favor a relationship with heat and sweating, as suggested by some authors. To our knowledge, this case of TAD is the first documented one in Taiwan. The rare reported cased of TAD in Taiwan might be due to low prevalence of this disorder among Orientals and/or to unfamiliarity with it. When confronted with cases of TAD, serial sectioning of the biopsy specimen is suggested to delineate the association of the lesions with the acrosyringium. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。