頁籤選單縮合
題名 | Collagen as Drug Carrier for Deep Sternal Wound Infection after Open Heart Surgery=開心手術後使用膠原蛋白做為深部胸骨感染之抗生素攜帶者 |
---|---|
作者 | 葉集孝; 林萍章; 朱肇基; Yeh, Chi-hsiao; Lin, Pyng-jing; Chu, Jaw-ji; |
期刊 | 長庚醫學 |
出版日期 | 20010700 |
卷期 | 24:7 2001.07[民90.07] |
頁次 | 頁451-454 |
分類號 | 416.262 |
語文 | eng |
關鍵詞 | 膠原蛋白; 開心手術; 深部胸骨感染; 萬古黴素; Collagen; Open heart surgery; Deep sternal wound infection; Vancomycin; |
英文摘要 | How to optimally treat deep sternal wound infection after open wound infection remains controversial. Biomaterial advances have made local antibiotics-releasing systems a promising alternative for treating deep sternal wound infection. Two patients with deep sternal wound complications were treated with radical wound debridement, sternal refixation, retrosternal suction drainage, bilateral pectoralis major muscle flaps and placement of collagenous drug carriers loaded with vancomycin underneath, above and between the sternal edges. No treatment failure and death occurred in these patients. There were no side effects, treatment failures or deaths after adjuvant treatment with collagenous vancomycin. Preliminary results of these 2 case studies demonstrate the feasibility of successfully treating deep sternal wound infections with collagenous vancomycin in combination with surgical debridement. This technique is easily performed, reliable and safe. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。