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頁籤選單縮合
題名 | Myxoma of the Gingiva: A Case Report and Literature Review=牙齦粘液腫瘤--病例報告及文獻回顧 |
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作者 | 張士灝; 李錦輝; 陳朝寶; 郭松泊; Chang, Shih-hao; Lee, Kam-fai; Chan, Chiu-po; Kuo, Song-bor; |
期刊 | 長庚醫學 |
出版日期 | 20011200 |
卷期 | 24:12 2001.12[民90.12] |
頁次 | 頁826-831 |
分類號 | 416.94 |
語文 | eng |
關鍵詞 | 黏液瘤; 齒齦腫瘤; 免疫組織化學; Myxoma; Gingival neoplasms; Immunohistochemistry; |
中文摘要 | 於口腔及鄰近之軟組織黏液瘤極為罕見,過文獻僅有兩例位於齒齦之黏液瘤。此種腫瘤之組織生成並不確定。而過病例報告對齟齦液瘤,病患右下第三大臼齟近內近舌剷齟齦有一1.5×1.2×1公分大小略呈橢圓之緻密瘤狀突起,X光檢查正常。腫瘤切陰後八個月並無復發。切除性病理切片顯示怖疏炎性細胞浸潤及由血管纖維與液狀液體組成之基質,初步顯示為口腔黏液瘤。進一步利用阿辛藍、過碘酸-Schiff、網蛋白、S-100蛋白、網格蛋白、肌間線蛋白、黏液洋紅、平滑肌特異蛋白等組織化學及免疫組織化學染色法進行鑑別診斷,結果顯示S-100蛋白、肌間線蛋白、平滑肌特異蛋白等染色結果為彫;而阿辛藍、過碘酸-?Schiff、網蛋白、網格蛋白、黏液洋紅等染色結果為正。此一結果顯示此腫瘤為一由酸性黏多醣組成之黏液瘤之診斷。由於此病灶之位置及與阻生齒之關聯,吾人無法完全排除其牙周韌帶細胞來源之可能性,尚需進一步研究以釐清其細胞來源及組織生成。由於其他於齒齦,以及臨床表徵易與齒齦炎性增生或齒纖維瘤混淆,因而使牙周病醫師應了解並有能力診斷治療此一腫瘤。 |
英文摘要 | soft tissue myxomas of the oral and para-oral tissue are extremely rare. Only two cases of myxoma of gingiva have been reported in the literature. The histogenesis of these lesions remains obscure. We report a case of gingival myxoma in a 37-year-old man. A firm ovoid soft tissue mass measuring 1.5×1.2×1cm in size noted at the mesio-lingual gingival of a partially impacted right mandibular third molar. Radiographic examination revealed an impacted mandibular third molar with normal radiographic bony consistency of the mandible. Excisoinal biopsy was performed with no evidence of recurrence after 8 months. Histological examination showed stromal mass composed of myxoid-like fluid in fibrovascular stroma and scanty inflammatory cell infiltration, suggesting myxomas of the oral soft tissues and jaws. Immuniohistochemical stains with S-100 protein, desmin and smooth muscle specific actin yielded negative results, and those with alcian blue, periodic-acid-Schiff, mucicarmine, vimentin and reticulin were positive. Tumor cells of mesenchymal origin without neurogenic or muscular derivations and myxoid matrix composed of acid mucopolysaccharides in this lesion further confirmed the diagnosis of myxoma. Periodontal ligament origin cannot be completely excluded due to tumor location and its association with an impacted molar. However, further studey is necessary to tumor location and its association with an impacted molar. However, further study is necessary to clarify the origin and histogenesis of these lesions. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。