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| 題 名 | Bronchopulmonary Carcinoids--An Analysis of 26 Cases=支氣管肺類癌--二十六例之病例分析 |
|---|---|
| 作 者 | 林巧峰; 謝致政; 劉家全; 黃敏雄; | 書刊名 | 胸腔醫學 |
| 卷 期 | 16:4 2001.12[民90.12] |
| 頁 次 | 頁228-235 |
| 分類號 | 415.468 |
| 關鍵詞 | 支氣管肺類癌; 典型類癌; 非典型類癌; Bronchopulmonary carcinoid; Typical carcinoid; Atypical carcinoid; |
| 語 文 | 英文(English) |
| 中文摘要 | 支氣管肺類癌大約佔所有原發性肺腫5%。支氣管肺類癌之本質雖較肺癌為良性,然其仍具局部侵犯,區域淋巴較移,和遠處轉移之能力。自1977至1982年,臺北榮民總醫院胸腔外科收集了26個於本院接受手術之支氣管肺類癌病人。這些病人及被為典型及非典類癌兩類。我自迴溯性分析了這些病人的臨床診斷率、手術結果及預後因子。 在這26個病人中,22個病人為典型支氣管肺類癌,4個病人為非類型支氣管肺類癌。十六個病人為男性;十個病人為女性。年齡分佈自34歲至79歲。平均年齡為57.4歲。吸煙的有十個病人。最常見的症狀是咳嗽(76.9%)其次為咳血(38.5%)。兩個病人有類癌症候群。腫瘤主要位在右中棄(34.6%),7.%的腫瘤位於右側肺葉。在非典型類癌之病人中有一人有肝臟轉移。大多數的病人接受肺葉切除術。沒有任何手術併發症或者死亡。有13個病人術後存活超過5年,其中有8人超過10年。預後因子分析包含了臨床症狀,手術方,病理形態,淋巴節和遠處轉移。在我們的研究中只有遠處轉移會影響預後。 從我們二十二年的經驗中,我們建議對支氣管肺類癌採取手術切除。對非典型支氣管肺類癌,甚至淋巴節或遠處轉移的病人,採取更積極的治療方法。 |
| 英文摘要 | Bronchopulmonary carcinoids comprise about 5% of all primary tumors of the lung. Though more benign in nature, bronchopulmonary carcinoids have a potenitial for local invasion, reigional nodal involvement, and distant metastasis. From 1997 to 1998, 26 patients were admitted to our section with surgical proof of bronchopulmonary chacinoids. They were classified into two subtypes: typical and atypical carcinoids. We retrospectively analyzed the clinical data, diagnostic rate, surgical results, and prognostic factors. Of these 26 patients, 22 patients had typical carcinoids and 4 atypical. The mean age was 57.4 years, with a range of 34 to 46 years. Sixteen were male and 10 were female. Ten patients were smokers. The most common presenting symptom was cough (76.9%), followed by hemoptysis (38.5%). Corcinoid syndrome was observed in 2 patients. The tumors were predominantly localized in the right middle lobe (34.6%), with a right-sided preference in 73% of the cases. Lobectomy was the treatment of choice for most of our patients. No surgical morbidity or mortality was noted. Eight patients had a 10-year disease-free survival, and 13 patients had a 5-year disease-free survival. The prognostic factors that were analyzed included clinical presentation, surgical method, pathological subtype, regional lymph mode metastasis, and distal metastasis. Only distal metastasis could influence survival. In conclusion, we believe that surgical resectiojn for typical carcinoids is sufficient; but a more aggressive treatment of atypical carchnoids is needed, especially in cases with nodal or distal metastasis. |
本系統中英文摘要資訊取自各篇刊載內容。