頁籤選單縮合
題名 | 2009~2013年臺灣地區登革熱病例採檢結果分析=Laboratory Characteristics of Dengue Fever in Taiwan during 2009~2013 |
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作者 | 賴淑寬; 陳主慈; 周玉民; Lai, Shu-kuan; Chen, Chu-tzu; Chou, Yu-min; |
期刊 | 疫情報導 |
出版日期 | 20150908 |
卷期 | 31:17 2015.09.08[民104.09.08] |
頁次 | 頁431-439 |
分類號 | 415.85 |
語文 | chi |
關鍵詞 | 登革熱; 確診陽性率; 綜合檢驗結果; 敏感度; |
中文摘要 | 世界衛生組織已於2012年宣布登革熱為目前傳播速度最快的蟲媒傳染病,臺灣處於熱帶及亞熱帶地區,鄰近東南亞國家均為登革熱高風險區,登革熱確定病例發生率亦為我國急性傳染病之冠,每年投入之防疫資源及人力不可勝數,為因應未來可能的大規模流行疫情,故進行登革熱病例採檢結果分析,重新檢視檢驗政策施行效益。經分析2009–2013年之登革熱病例發現:(一)醫療院所通報之5年平均確診率,本土病例與境外移入病例之差異,具統計上顯著意義;(二)約93%的登革熱病例,以一採檢體綜合檢驗結果即可進行研判,其中約40%為確定病例;需二採或三採之通報病例,約73%為登革熱確定病例;(三)登革熱確定病例75%以一採PCR或NS1陽性判定;PCR或NS1檢驗方法一採敏感度介於70.5–76.9%,IgM或IgG檢驗方法二採敏感度介於78.0%–95.4%。本研究結果顯示,落實於流行季前進行醫療院所的訪視及醫師再教育訓練,提醒醫師登革熱的診斷與通報,以提高確診率;對需進行二採之通報病例,在防疫量能允許之情況下,建議視為確定病例進行緊急防治措施,避免疫情擴大;加強提醒民眾有疑似症狀儘速就醫或自主通報,有利於以PCR或NS1檢驗快速判定,降低需進行二採的比例,節約檢驗資源亦避免疫情擴散。 |
英文摘要 | World Health Organization has declared dengue is the most rapidly spreading mosquito-borne disease in 2012. Located in subtropical regionand frequently in contact with dengue high-risk Southeast Asian countries with dengue ranks as the most important acute infectious disease, Taiwan has spent innumerable resources and manpower in dengue prevention and control. Since huge dengue epidemic might occur in the future, laboratory analysis of dengue cases wastaken for re-examining the benefits of laboratory diagnosis. The results showed in the followings: (1) On five-year average positive rate of medical institutions, the difference between imported dengue cases and indigenous casesis statistically significant; (2) 93% of dengue cases could be determined by first specimen result, and 40% of them were confirmed cases; 73% of dengue cases collected more than one specimen were confirmed cases; and (3) 75% of dengue confirmed cases were determined by PCR or NS1 in first specimen. The sensitivity of PCRor NS1 test in the first specimen was between 70.5% and 76.9%, and the sensitivity of IgM or IgG test in the second specimen was between 78.0% and 95.4%. These findings indicated that it is necessary to continually implement medical institutesvisits and physicians education training before epidemic seasons to remind physicians about dengue symptoms in order to improve positive rate; if the diagnosis is uncertain with the first specimen but due to the necessity of urgent preventive measures for reducing the risk of disease spreading, with sufficient public health resources, a second specimen shall be recommended. Moreover, it will cut down laboratory expenses and avoid disease spreading by strengthening the public health education in seeking medical treatment and self-report with suspected symptoms in no time, since diagnosis can be determined by rapid PCR or NS1 test and reducing second specimen collection. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。