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題名 | 高燒潰瘍壞死性Mucha-Habermann氏症--病例報告=Febrile Ulceronecrotic Mucha-Habermann's Disease--Report of a Case |
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作者 | 謝其娟; 邱耀堃; 何宜承; 黃純真; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 19:3 2001.09[民90.09] |
頁次 | 頁233-242 |
分類號 | 415.73 |
關鍵詞 | 高燒潰瘍壞死性Mucha-Habermann氏症; 急性苔蘇痘狀糠疹; Febrile ulceronecrotic Mucha-Habermann's disease; Pityriasis lichenoides et varioliformis acuta; PLEVA; |
語文 | 中文(Chinese) |
中文摘要 | 吾人在此報告一febrile ulceronecrotic Mucha-Habermann’s disease之病例。這是一個8歲男孩一開始是以全身性丘疹水泡合間斷性高燒來表現,此現象在一個月內反覆發作兩次,初期診斷為出血性水痘,給與Acyclovir及抗生素的治療,新的膿皰仍不斷在肢端出現,且舊的病灶持續潰瘍壞死,且合併全身性症狀(頭痛,全身倦怠,關節酸痛,腹痛,腹瀉),我們在膿皰處作一皮膚切片,但並無確切診斷,皮膚病灶漸形成結痂脫屑斑塊及疤痕,病人出院後在小兒科門診追蹤,接受口服Dicloxacillin之治療。兩個月後,在軀幹處出現新的脫屑斑塊,我們又作了一次皮膚切片,病理下可符合為一急性苔蘚痘狀糠疹。綜合以上臨床及病理我們診斷此一病人為一febrile ulceronecrotic Mucha-Habermann’s disease。 |
英文摘要 | Herein, we report on a case of febrile ulceronecrotic Mucha-Habermann’s disease (FUMHD). An eight-year-old boy, who presented with generalized hemorrhagic papulo-vesicles associated with intermittent high fever initially, experienced similar and recurrent episodes during the subsequent one month perioid. Initially, the patient was clinically diagnosed as suffering from hemorrhagic chicken pox, and he received acyclovir and antibiotics treatment. Unfortunately, new pustules continued to appear at distal extremities and old lesions exhibited ulcero-necrotic changes accompanied by systemic symptoms (headache, malaise, arthralgia, abdominal pain and diarrhea), and, accordingly, a skin biopsy was performed at the site of one of the pustules, although without any definite diagnosis being made. Following further supportive treatment, lesions became scaling plaques with subsequent scar formation, and the patient was discharged and followed up with oral dicloxacillin in our pediatric department. Two months later, some new scaling plaques had occurred on the trunk, and a further skin biopsy was performed, the result of which was compatible with a diagnosis of pityriasis lichenoides et varioliformis acuta. We therefore concluded that this patient was a case of febrile ulceronecrotic Mucha-Habermann’s disease, according to his past clinical course and histopathological finding. |
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