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題名 | Linear Branching Echogenicities in the Basal Ganglia and Thalami=基底核及視丘之樹枝狀高超音波影像 |
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作者 | 王漢溪; 簡志澔; 廖明厚; 吳俞哖; 蘇育賢; Wang, Han-hsi; Chien, Chih-hao; Liao, Min-hou; Wu, Yu-nian; Su, Yu-hsien; |
期刊 | Clinical Neonatology |
出版日期 | 19981200 |
卷期 | 5:2 1998.12[民87.12] |
頁次 | 頁13-18 |
分類號 | 417.143 |
語文 | eng |
關鍵詞 | 基底核; 視丘; 超音波影像; Basal ganglia; Vasculopathy; Brain ultrasound; Infants; |
英文摘要 | Echogenic vasculature in the basal ganglia and thalami of neonatal brain have been associated with congenital infections such as cytomegalovirus (CMV), rubella, and syphilis, trisomy 13 syndrome, Down syndrome, maternal drug use, neonatal asphyxia, nonimmune hydrops, and fetal alcohol syndrome. This abnormality is believed to result from necrotizing vasculits with subsequent mineralization. In our study, we encountered 8 small infants whose cranial sonograms revealed linear, branching echogenecities in the basal ganglia and thalami. These echogenecities had the appearance of vascular structures. One premature triplet, gestational age 33 weeks, had a bilateral grade Ⅲ intraventricular hemorrhage with post-hemorrhagic hydrocephalus. Another premature infant had a patent ductus arteriosus with congestive heart failure. The others were term infants and the clinical diagnoses included congenital rubella syndrome, bilateral renal hypoplasia with arthrogryposis, suspected pseudohypoparathyroidism, multiple congenital anomalies, urinary tract infection, and gastroesophageal reflux. One case of rubella and 2 cases of CMV infection were documeted by serology. Karyotyping was performed in 4 patients and all were normal. Duplex Doppler sonography in 5 infants demonstrated an arterial waveform and confirmed the vascular nature of the echogenecities. computed tomography was done in 3 infants, of which two had corresponding calcification in the basal ganglia and thalami. The average postnatal age at detection of sonographic abnormalities was 45 dyas (rang 5-86 days). In 2 patients, the abnormalities were found on follow-up sonogram after previous negative examinations. In our limited experience, there seems to be more underlying diseases and conditions with linear, branching echogenecities in the basal ganglia and thalami than mentioned in previous reports. There is evidence that some of these conditions develop in postnatal life. The prognosis of the developmental outcome in these patients seems to depend on the underlying causes. |
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