頁籤選單縮合
題名 | Novel Quinazolinones from 2-Cyanomethyl-3-Phenyl-4(3H)-Quinazolinone= |
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作者 | El-Feky,Said A.; |
期刊 | 中華藥學雜誌 |
出版日期 | 19981000 |
卷期 | 50:5 1998.10[民87.10] |
頁次 | 頁305-312 |
分類號 | 418.4 |
語文 | eng |
關鍵詞 | 4-(3H)-quinazolinones; Thiourea; 1,2,4-oxadiazoles; Pyrazolo[1,5-a]quinazolinone; |
英文摘要 | Starting from 2-cyanomethyl-3-phenyl-4-(3H)-quinazolinone (1), 2-[mercapto(cyano) methylene]-3-phenyl-1, 2, 3, 4-tetrahydroquinazolin-4-one (5),2-amino-4-phenylpyrazolo[1, 5-a]quinazolin-5-(4H) -one (8), and 2-(methyl or phenyl-1,2,4-oxadiazol-3-ylmethyl)-3-phenyl-4-(3H)-quinazolinones (9) and (11) were prepared via the α-bromo derivative 2 and the amide oxime 6. The new compounds were characterized by elemental analysis, H NMR, IR and alternative synthesis in same cases. |
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