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題 名 | Bacterial Translocation to the Mesenteric Lymph Node in Patients with Colorectal Cancer=大腸癌患者細菌遷移至腸繫膜淋巴結的機率 |
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作 者 | 許自齊; | 書刊名 | 中華民國外科醫學會雜誌 |
卷 期 | 33:3 民89.05-06 |
頁 次 | 頁107-111 |
分類號 | 416.245 |
關鍵詞 | 大腸癌; 細菌遷移; 腸繫膜淋巴結; Bacterial translocation; Colorectal cancer; Mesenteric lymph node; |
語 文 | 英文(English) |
中文摘要 | 造成細菌遷移的因素很多。結腸直腸癌的患者常有這些因素如營養不良,免疫抑制及腸阻塞等現象。這一研究的目的是來探討結腸直腸癌的患者是否會有細菌遷移的高機率。這一系列包括了由民國84年1月至民國87年8月的286例接受結腸直腸癌手術的患 者。其中有141位男性及145位女性。年齡由13歲至92歲不等(平均為62.34歲)。有164例為直腸癌,55例為乙狀結腸癌,12例為降結腸癌, 20例為橫結腸癌, 36例為升結腸癌,4例為盲腸癌。35例患者合併有急性結腸阻塞。剖腹探查尚未分割結腸前即立刻做腸繫膜淋巴結的培養。共有9例(3.15%)的培養為陽性。而有2例(5.71 %)培養起陽性的出現在合併有腸阻塞的病例,這一機率遠高於沒有腸阻塞的病例(2.79%)。培養出的細菌均為腸道內常見的菌種。雖然結腸直腸癌患者併有細菌遷移的機率不很高,但是在併有腸阻塞的病例因為併有細菌遷移的機率較高,所以手術後投與較長期的抗生素是為合理的。 |
英文摘要 | There are many etiological factors associated with bacterial translocation. Patients with colorectal cancer are frequently associated with a few of these factors such as malnutrition, immunosuppression, and obstruction. This study was designed to determine whether patients with colorectal cancer have high incidence of bacterial translocation, 286 patients operated for colorectal cancer from January 1995 to August 1998 were entered in this study. There were 141 males and 145 females. Ages ranged from 13 to 92 years old (average 62.34 years old). The distribution of tumor sites was listed as follows: 164 in the rectum, 55 in the sigmoid, 12 descending colon cancer, 20 transverse colon cancer, 36 ascending colon cancer, and 4 in the cecum. Thirty five patients had acute colonic obstruction. Culture of the mesenteric lymph node was taken prior to the dissection of the colon. There were nine (3.15%) positive cultures. Positive culture occured in two patients with obstrution, higher than non-obstructive patients (5.71% vs 2.79%). Although bacterial translocation is not high in patients with colorectal cancer, higher incidence of translocation to mesenteric lymph node in obstructive group may warrant administration of antibiotics longer than just for prophylaxis. |
本系統中英文摘要資訊取自各篇刊載內容。