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題 名 | Conformational Analysis of 1,2-Di-O-Octanoyl-Ethylene-Glycerol during Aggregation |
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作 者 | 林家立; 呂君萍; | 書刊名 | Journal of the Chinese Chemical Society |
卷 期 | 47:2 2000.04[民89.04] |
頁 次 | 頁301-306 |
分類號 | 348.223 |
關鍵詞 | Conformational analysis; Stereochemistry; Micelle; Lipid analogue; |
語 文 | 英文(English) |
英文摘要 | Conformational analysis of 1,2-di-O-octanoyl-ethylene-glycerol during aggregation by 600 MHz 1H NMR is described. In monomeric states, 1,2-di-O-octanoyl-ethylene-glycerol exists in 75% anti-conformer and 25% gauche-conformer. The first critical micelle concentration of 1,2-di-O-octanoyl-ethylene-glycerol is calculated to be 4.5 mM. In micellar states, 1,2-di-O-octanoyl-ethylene-glycerol exists in 25% anti-conformer and 75% gauche-conformer. When the concentration is greater than 10 mM, 1,2-di-O-octanoyl-ethylene-glycerol probably aggregates to become the larger micelle, micelle II. In the second micellar state, 1,2-di-O-octanoyl-ethylene-glycerol only exists in gauche-conformer. |
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